In vivo sodium tungstate treatment prevents E-cadherin loss induced by diabetic serum in HK-2 cell line
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منابع مشابه
Beta Cell Protective Effects of Sodium Tungstate in Streptozotocin-Induced Diabetic Rats: Glycemic Control, Blockage of Oxidative Stress and Beta Cell Histochemistry
Background: Diabetes is a major public health problem. The development of new therapies that are able to improve glycemia management and even to cure diabetes is of great interest. In this study, protective effects of sodium tungstate against STZ-induced beta-cell damages were investigated. Methods: Sixty rats were divided into six groups: control, diabetic, sodium tungstate treated diabetic r...
متن کاملTungstate treatment improves Leydig cell function in streptozotocin-diabetic rats.
Oral administration of sodium tungstate to adult male streptozotocin-diabetic rats for 3 months normalized serum levels of glucose, insulin, luteinizing hormone, and follicle-stimulating hormone. These effects were accompanied by an increase in reproductive performance, which was related to a strong improvement in Leydig cell function markers, such as the recovery of the number of Leydig cells ...
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Objective(s): Valproic acid (VPA) has proven to be as one of the most promising useful drug with anticancer properties.In this study, we investigate the VPA effects on E-cadherin expression in HeLa, TC1, MKN45, and HCT116 cell lines. This study assesses the effects of VPA on human papillomavirus E7 expression in HPV positive cell lines. Materials and Methods: Cell lines were treated by2 mmol/...
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Background: The aim of this study was to evaluate the possible protective effect of sodium selenite on serum, liver, and kidney antioxidant enzymes activities in alloxan-induced type 1 diabetic rats. Methods: Forty Sprague-Dawley male rats were randomly divided into four groups; Group one as control, Group two as sham-treated with sodium selenite by 1 mg/kg intraperitoneal (i.p.) injections ...
متن کاملBiochemical and Histological Study of Protective Effect of Sodium Tungstate on Oxidative Stress Induced by Streptozotocin in Pancreas of Diabetic Rats
Purpose: The aim of this study was evaluation of effects of sodium tungstate on oxidative stress in pancreas of streptozotocin induced diabetic rats. Materials and Methods: Sixty mature Wistar male rats (Age: 2-3 month) were selected and divided into six groups randomly (n=10). Control (C), STZ-induced diabetic (D), STZ-induced diabetic rats were treated by sodium tungstate (1 mg/ml) in drinkin...
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ژورنال
عنوان ژورنال: Journal of Cellular Physiology
سال: 2015
ISSN: 0021-9541
DOI: 10.1002/jcp.24974